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Table 1 Absolute outcome and prevented cases for different ages at vaccination in the base case scenario

From: Assessing the potential effects and cost-effectiveness of programmatic herpes zoster vaccination of elderly in the Netherlands

  60 years 65 years 70 years 75 years 80 years
Before vaccination:      
Cases HZ 26845 15513 11093 7630 4769
Cases PHN 4639 2936 2351 1857 1370
Hospitalization 320 205 163 128 89
1 day visit hospital 1102 683 515 363 210
Deaths 30.7 20.9 18.6 17.6 16.5
Direct costs* €2217577 €1527388 €1306022 €1100313 €847884
Indirect costs* €1241555 €0 €0 €0 €0
QALYs lost* 3024 2024 1703 1402 1060
After vaccination: (75% coverage)      
Nr. of vaccinees 175925 115943 94354 80712 58724
Vaccination costs** €14680941 €9675443 €7873841 €6735416 €4900518
Cases HZ 22512 12496 9201 6277 4299
Cases PHN 4222 2581 2071 1603 1257
Hospitalization 292 178 141 107 81
1 day visit hospital 966 563 426 294 188
Deaths 30.5 20.6 18.1 16.4 15.4
Direct costs* €1832919 €1219724 €1082777 €902727 €760458
Indirect costs* €541068 €0 €0 €0 €0
QALYs lost* 2671 1724 1350 1133 921
Prevented:      
Cases HZ 4334 3017 1892 1352 471
Cases PHN 417 355 280 254 113
Hospitalization 28 27 21 20 9
1 day visit hospital 136 120 89 70 22
Deaths 0.2 0.3 0.5 1.2 1.1
Direct costs* €384658 €307664 €223245 €197586 €87427
Indirect costs* €700487 €0 €0 €0 €0
QALYs lost* 353 300 352 269 140
  1. * Costs are discounted with 4% and QALYs with 1.5%
  2. ** Vaccination costs are based on a vaccine price of €77, application costs of €4.80 per vaccination and coordination costs of €1.65 per vaccination