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Table 3 Alert Interventions to decrease benzodiazepine use

From: Improving the use of benzodiazepines-Is it possible? A non-systematic review of interventions tried in the last 20 years

Study Location Intervention Design: Alert Interventions targeted at GPs Study Design and Size Result Follow up
Simon et al, 2006 [72] USA - Oregon & Washington 1 = age Specific (> 65 years) alert for long acting BZs. 2 = alerts + academic detailing (group education + follow-up letter). Cluster randomized trial 239 clinicians No sig decrease in prescribing to elderly. No difference between alerts (decrease of 3.0 dispensed medications per 10,000 members) and alerts + academic detailing (decrease of 19.7 dispensed medications per 10,000) 18 months post intervention
Monane et al, 1998 [73] America 1 = age specific (> 65 years) alert system at pharmacy (mail order and retail). If medication is deemed to be inappropriate then conversation between pharmacist and prescriber occurred. 2 = control. Population based cohort 2.3 million people >65 years filled a script during study period Sig difference between intervention (40% of cases) and control (2%) for the change of prescriptions for long acting BZs. Sig difference between control (2%) and intervention (25%) for change to prescriptions of short acting BZs that exceeded the maximum daily dose. 1 year study (measured total number of changes over 1 year)
  1. BZ = benzodiazepine, Sig = statistically significant (p < 0.05), GP = General Practitioner