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Table 1 Comparison of included studies

From: Patients' age as a determinant of care received following acute stroke: A systematic review

First author year Country language Sample size Study's design & primary objective Sample demographics Age ranges Confounders considered Acute care processes indicators audited (Level 1) CASP quality score
Bhalla 2004 [8] Europe 10 countries English 1847 Observational, retrospective. To estimate the structure & process of care, and independent factors associated with 3 month mortality and functional outcomes in patients aged >75 yrs compared to younger stroke patients Mean age 70.2 (SD 12.3) Age range 34-93 <75, ≥75 Age, Gender, Pre-stroke function, Previous home situation, Stroke type, Stroke severity, Stroke unit/other, Comorbidities CT head scan, Angiography, Stroke unit care, Carotid imaging. 8
Di Carlo 1999 [9] Europe 7 countries English 4499 Observational, prospective. To evaluate stroke features, hospital resource usage and functional outcome in patients aged ≥80 years compared with the younger age groups. Mean age 71.8 (SD 12.6) Age range 13-102 Females 50.2% Stroke types: Infarct 60.9% Haemorrhage 10.3% <80, ≥80 Age, Gender, Pre-stroke function, CT head scan, Angiography. 7
Fairhead 2006 [20] UK English 681004 Observational, retrospective. To evaluate the investigation of carotid stenosis in older patients with TIA and stroke. Nil reported <80, ≥80 Age, Gender, Stroke type, Degree of stenosis Angiography, Carotid imaging. 8
Heidrich 2007 [21] Europe 10 countries English 1721 Observational, retrospective. To investigate variations in use of diagnostic procedures across selected European acute stroke hospitals. Mean age 69 (SD 12.9) Females 53.6% Stroke types: infarct 57% Haemorrhage 10.3% SU care 14.8% <65, 65-74, 75-84, ≥85 Age, Stroke severity, Comorbidities, Delay to hospital, Geography CT head scan. 9
McKevitt 2005 [11] UK English 1635 Observational, prospective. To determine whether patterns of clinical service provision differ by age, sex, socioeconomic status (SES) or ethnicity Mean age 71.6 (SD 14.2) Females 51.3% <65, 65-74, 75-84, ≥85 Age, SES, Gender, Ethnicity, Pre- post-stroke morbidity, Disability, Stroke severity, Stroke unit/other, Cognition CT head scan Stroke unit care 9
McNaughton 2003 [19] New Zealand English 181 Observational, prospective. To test whether current measures of stroke processes are related to stroke outcome Mean age 74.4 (SD 12) Females 53% Stroke types; Infarct 86.1% Haemorrhage 9.9% <75, >75 (sic) Age, Ethnicity, Stroke type, Admission function, Discharge function CT head scan, Swallow screen, 6
Palnum 2008 [10] Denmark English 29549 Observational, retrospective. To examine the fulfilment of stroke quality-of-care criteria according to age and the possible impact of age-related differences on mortality. Nil reported <65, 65-80, >80 Age, Gender, Pre-stroke function, Previous home situation, Stroke severity, Comorbidities CT head scan, Stroke unit care, Antithrombotic/antiplatelet therapy, Anticoagulants for AF, 10
Rudd 2007 [7] UK English 8718 Observational, retrospective. To determine whether access to high-quality stroke care is affected by the age or gender of patients, or by weekend admissions SU care 46% <65, 65-74, 75-84, ≥85 Age, Gender, Stroke unit/other, Weekend admission CT head scan, Stroke unit care, Carotid imaging, Asprin commenced early, Antithrombotic therapy by discharge, Risk factor information to patient, Anticoagulants for AF, Antihypertensive therapy, Swallow screen. 9
Saposnik 2009 [22] Canada English 3631 Observational, prospective. To determine whether access to stroke care, delivery of health services, and clinical outcomes after stroke are affected by age Mean age 72.0 Females 47.8% Previous NH 5.6% Comorbidities: Low CCI ≤1 65.8% <59, 60-69, 70-79, >80 Age, Gender, Stroke unit/other, Stroke severity, Comorbidities Thrombolysis therapy, Stroke unit care, Carotid imaging, Antithrombotic/antiplatelet therapy, Anticoagulants for AF, Antihypertensive therapy, Swallow screen, 10
  1. Table legend: SU = stroke unit SD = Standard deviation UK = United Kingdom CCI = Charlson Comorbidity Index