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Table 1 Descriptive statistics and univariate logit estimates

From: Determinants of generic drug substitution in Switzerland

  Frequency Substitution rate Odds ratio 95%CI
OUTCOME VARIABLE Use of a generic drug (yes = 1, no = 0) 0.313    
CANTONS     
   Aargau (reference) 0.372 0.433   
   Vaud 0.329 0.350 0.706 [0.689, 0.722]
   Ticino 0.299 0.124 0.186 [0.181, 0.192]
PATIENTS' VARIABLES Female:     
   no (reference) 0.378 0.317   
   yes 0.622 0.311 0.972 [0.952, 0.993]
Age:     
   0-19 0.100 0.411 2.057 [1.986, 2.131]
   20-39 0.158 0.410 2.050 [1.989, 2.112]
   40-59 0.250 0.344 1.543 [1.502, 1.585]
   60-79 (reference) 0.356 0.254   
   80+ 0.136 0.228 0.868 [0.838, 0.900]
Optional health insurance deductible:     
   no (reference) 0.619 0.344   
   yes 0.381 0.264 0.685 [0.671,. 0.700]
Out-of-pocket participation:     
   no (reference) 0.396 0.241   
   yes 0.604 0.361 1.777 [1.740, 1.816]
Treatment complexity:     
   1-5 drugs 0.215 0.424 1.429 [1.390, 1.469]
   6-10 drugs (reference) 0.290 0.340   
   11-15 drugs 0.223 0.280 0.757 [0.735, 0.779]
   16-20 drugs 0.139 0.246 0.634 [0.613, 0.657]
   21+ drugs 0.133 0.202 0.491 [0.473, 0.509]
PHYSICIANS' VARIABLES Specialist prescriber:     
   no (reference) 0.777 0.314   
   yes 0.223 0.310 0.978 [0.955, 1.003]
Hospital prescriber:     
   no (reference) 0.880 0.325   
   yes 0.120 0.225 0.603 [0.583,.0.624]
SUBSTITUTION GROUPS' VARIABLES Number of generics     
   1-2 (reference) 0.333 0.153   
   3-4 0.260 0.374 3.322 [3.225, 3.422]
   5-6 0.298 0.415 3.934 [3.823, 4.049]
   7+ 0.110 0.382 3.430 [3.305, 3.559]
Number of treated patients:     
   1-1000 (reference) 0.361 0.263   
   1001-2000 0.259 0.322 1.334 [1.299, 1.370]
   2001-3000 0.122 0.223 0.803 [0.774, 0.834]
   3001+ 0.257 0.418 2.017 [1.965, 2.070]
Price of brand medication:     
   1st quintile 0.189 0.327 1.000 [0.969, 1.031]
   2nd quintile 0.165 0.251 0.689 [0.666, 0.713]
   3rd quintile (reference) 0.239 0.327   
   4th quintile 0.187 0.328 1.002 [0.972, 1.034]
   5th quintile 0.220 0.321 0.972 [0.943,.1.001]
Relative price difference:     
   1st quintile 0.188 0.200 0.599 [0.578, 0.620]
   2nd quintile 0.200 0.347 1.267 [1.227, 1.308]
   3rd quintile (reference) 0.206 0.295   
   4th quintile 0.204 0.301 1.029 [0.996, 1.062]
   5th quintile 0.203 0.416 1.701 [1.649, 1.754]
Administration mode:     
   Oral (reference) 0.839 0.328   
   Topic 0.095 0.285 0.817 [0.788, 0.847]
   Inhalation, nasal & ophthalmic 0.032 0.046 0.099 [0.087, 0.112]
   Parenteral, rectal & vaginal 0.034 0.273 0.769 [0.726, 0.815]
Original with special galenic form:     
   no (reference) 0.862 0.338   
   yes 0.138 0.160 0.373 [0.359, 0.386]
At least one drug sold under license:     
   no (reference) 0.818 0.316   
   yes 0.182 0.300 0.929 [0.904, 0.954]
Multiple package sizes:     
   no (reference) 0.575 0.294   
   yes 0.425 0.339 1.232 [1.207, 1.258]
Observations 173,212