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Table 3 National Institute for Health and Care Excellence (NICE) guidelines - risk factors and interventions to prevent delirium 17

From: Developing and implementing an integrated delirium prevention system of care: a theory driven, participatory research study

Risk factors
Age 65 years or older
Cognitive impairment (past or present) and/or dementia
Current hip fracture
Severe illness (a clinical condition that is deteriorating or is at risk of deterioration)
Interventions to prevent delirium
Clinical factor Preventative intervention
Cognitive impairment or disorientation • Provide appropriate lighting and clear signage. A clock (consider providing a 24-hour clock in critical care) and a calendar should also be easily visible to the person at risk.
• Reorientate the person by explaining where they are, who they are, and what your role is.
• Introduce cognitively stimulating activities (for example, reminiscence).
• Facilitate regular visits from family and friends.
Dehydration or constipation • Encourage the person to drink. Consider offering subcutaneous or intravenous fluids if necessary.
• Seek advice if necessary when managing fluid balance in people with comorbidities (for example, heart failure or chronic kidney disease).
Hypoxia • Assess for hypoxia and optimise oxygen saturation if necessary.
Immobility or limited mobility • Encourage the person to:
mobilise soon after surgery
walk (provide walking aids if needed – these should be accessible at all times).
• Encourage all people, including those unable to walk, to carry out active range-of-motion exercises.
Infection • Look for and treat infection.
• Avoid unnecessary catheterisation.
• Implement infection control procedures in line with ‘Infection control’ (NICE clinical guidance 2).
Multiple medications • Carry out a medication review for people taking multiple drugs, taking into account both the type and number of medications.
Pain • Assess for pain. Look for non-verbal signs of pain, particularly in people with communication difficulties.
• Start and review appropriate pain management in any person in whom pain is identified or suspected.
Poor nutrition • Follow the advice given on nutrition in ‘Nutrition support in adults’ (NICE clinical guidance 32).
• If the person has dentures, ensure they fit properly.
Sensory impairment • Resolve any reversible cause of the impairment (such as impacted ear wax).
• Ensure working hearing and visual aids are available to and used by people who need them.
Sleep disturbance • Avoid nursing or medical procedures during sleeping hours, if possible.
• Schedule medication rounds to avoid disturbing sleep.
• Reduce noise to a minimum during sleep periods.
  1. National Institute for Health and Clinical Excellence [17]. Adapted from CG 103 Delirium: diagnosis, prevention and management. London: NICE. Available from Reproduced with permission.