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Table 4 Sensitivity- analysis

From: An economic assessment of embryo diagnostics (Dx) - the costs of introducing non-invasive embryo diagnostics into IVF standard treatment practices

Clinical probabilities Range*     
p_Pregnancy_cSET (mean:0.091) Input value   ICER Difference
Diagnostic_eSET versus eSET 0.073 0.109 €15,481 €15,473 €8
DET versus Diagnostic eSET    €52,447 €52,603 €156
DET versus eSET    €25,553 €25,465 €88
p_Pregnancy_DET (mean:0.406) Input value   ICER Difference
Diagnostic_eSET versus eSET 0.323 0.4843 €15,477 €15,477 €0
DET versus Diagnostic eSET    Dominated** €28,826 > €28,826
DET versus eSET    €35,438 €22,235 €13,202
p_Pregnancy_eSET (mean:0.214) Input value   ICER Difference
Diagnostic_eSET versus eSET 0.1714 0.2572 €17,995 €20,750 €2,755
DET versus Diagnostic eSET    €39,559 €39,559 €0
DET versus eSET    €24,256 €29,352 €5,096
Costs      
c_diagnostic tests (mean: €400) Input value   ICER Difference Input value
Diagnostic_eSET versus eSET 320 480 €14,705 €16,249 €1,544
DET versus Diagnostic eSET    €54,596 €50,454 €4,142
DET versus eSET    €25,509 €25,509 €0
c_IVF_Medication (mean: €1570) Input value   ICER Difference
Diagnostic_eSET versus eSET €1,256 €1,884 €15,705 €15,249 €456
DET versus Diagnostic eSET    €52,966 €52,085 €881
DET versus eSET    €25,792 €25,220 €572
c_IVF_HospCare (mean: €325) Input value   ICER Difference
Diagnostic_eSET versus eSET €260 €390 €15,524 €15,430 €94
DET versus Diagnostic eSET    €52,616 €52,434 €182
DET versus eSET    €25,566 €25,447 €119
c_IVF_Laboratory (mean:€1314) Input value   ICER Difference
Diagnostic_eSET versus eSET €1,051 €1,577 €15,596 €15,358 €238
DET versus Diagnostic eSET    €52,328 €52,723 €395
DET versus eSET    €25,541 €25,478 €63
c_IVF_EmbryoTransfer (mean:310) Input value   ICER Difference
Diagnostic_eSET versus eSET €248 €372 €15,522 €15,432 €90
DET versus Diagnostic eSET    €50,314 €54,736 €4,422
DET versus eSET    €24,943 €26,075 €1,132
  1. *Range: probabilities: plus/minus 20% but between 0 and 1.
  2. **Diagnostic eSET is more effective and cost saving versus DET.