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Table 10 Example of a modified GRADE evidence profile summary of findings. Table 9 and 10 is what Table 1 and 2 became when including the improvements made based on the pilot study experience

From: Systems for grading the quality of evidence and the strength of recommendations II: Pilot study of a new system

Outcome SSRI Tricyclics Effect Quality Importance
    Relative (95% CI) Absolute   
Depression severity 5044 patients 4510 patients WMD 0.034 (-0.007 to 0.075) No difference Moderate Critical
Transient side effects 1948/7032 (28%) 2072/6334 (33%) RRR 13% (5% to 20%) 5 per 100 High Critical
Poisoning fatalities*** 1/100,000 per year of treatment 58/100,000 per year of treatment RRR 98% (97% to 99%) 6 per 10,000 Moderate Critical
  1. ***There is uncertainty about the baseline risk for poisoning fatalities.