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Table 3 Most frequently prescribed drugs that interact with CYP450 enzymes by ATC codes

From: Frequency and clinical relevance of potential cytochrome P450 drug interactions in a psychiatric patient population – an analysis based on German insurance claims data

  All patients (n = 1221)
Prescribed drugs by ATC codes Frequency Number of patients (%)
M01 – Anti-inflammatory/antirheumatic products 3313 713 (58.40)
N06 – Antidepressants 6249 635 (52.0)
N05 – Antipsychotics 5879 471 (38.58)
A02 – Drugs for acid-related disorders 3050 448 (36.69)
N02 – Analgesics 1473 250 (20.48)
J01 – Antibacterials for systemic use 247 146 (11.96)
C10 – Lipid-modifying agents 941 137 (11.22)
C08 – Calcium channel blockers 1195 131 (10.73)
R05 – Cough and cold preparations 165 100 (8.19)
N03 – Antiepileptics 523 80 (6.55)
  
Sum 25,211 N/A
  1. The relative frequency (n) and number of patients who were prescribed the drug (n, %) are shown. Note that patients could be prescribed several drug classes