Concept elicitation: Direct, focused questions
• “How would you usually treat patients with ACE inhibitor-induced angioedema?”
• “How do you decide when a patient is ready to be discharged? What symptoms do you evaluate? Do you weigh some symptoms more than others? How?”
• “On a scale from 0–4, with 0 being none; absence of symptoms and 4 being very severe, in your opinion what reduction would constitute a clinically meaningful improvement in each of the symptoms of an ACE inhibitor-induced angioedema attack?”
• Using the same scale (0 = none to 4 = very severe), to what level would they need to get to (for each symptom), in order to feel comfortable discharging them? Are some symptoms more important than others?