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Table 2 The association of Indiana’s opioid prescription emergency rules to daily Morphine Equivalent Dose (MED) per patient of different opioids dispensed in Indiana

From: The effects of state rules on opioid prescribing in Indiana

Drug Name Impact of policy Pre-policy Time Trend Post-policy time trend
All opioids −3.17*** −0.0021*** −0.0044***
hydrocodone −3.68*** −0.0038*** −0.0048***
oxycodone −2.03*** −0.0015*** −0.0133***
morphine −0.03 −.0101*** −0.0185***
methadone −6.19*** −.0026*** −0.0333***
fentanyl −1.15 −.0080*** −0.0169***
oxymorphone −3.11* −.0245*** −0.0142*
buprenorphine −.47 −.0022*** −0.0209***
hydromorphone −3.54** .0005 −0.0143*
  1. Coefficients and t-statistics from Interrupted Time Series Analysis. *p ≤ 0.10, **p ≤ 0.05, ***p ≤ 0.01