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Table 3 A description of concordant and discordant classifications for algorithm 12, the algorithm that maximized sensitivity and specificity

From: Validating an algorithm to identify metastatic gastric cancer in the absence of routinely collected TNM staging data

Variable M1 (n = 1107) Mnot (n = 1259)
+/+ +/− −/+ −/−
80% 20% 32% 68%
Age (years)
  < 50 12.5 10.6 7.4 5.8
 50–54 7.6 8.8 5.4 5.1
 55–59 8.9 8.8 9.2 8.5
 60–64 11.1 10.2 8.7 10.6
 65–69 13.2 11.9 13.6 11.8
 70-high 46.8 49.6 55.7 58
Female 35.9 39.4 33.2 34.5
Tumour Location
 Distal 30.4 37.2 37.6 37.7
 Entire 9.9 5.8 9.7 7.7
 GEJ 27.4 30.5 27.2 25.6
 Middle 17 14.2 12.6 16.3
 Proximal 10.6 6.6 8.2 8.5
 Unknown 4.8 5.8 4.7 4.2
Charlson Score
 No Prev Hosp 56.4 49.6 57.9 47.4
 0 29.7 33.2 26.2 29.9
 1 7.6 8.8 7.7 11
 2+ 6.2 8.4 12.9 10
Urban Residence 89.2 89.4 87.6 87.7
Community Income
 Lowest 20.2 23 22.5 20
 2 22.9 17.7 23.3 21.6
 3 20 23 18.3 20
 4 20.3 17.7 16.6 20.1
 Highest 16.5 18.6 19.3 17.9
T stage
Tis/T0/T1 1 4.8 2.4 16
T2 1 7.1 3.2 13.8
T3 3.2 20.8 7.7 15.3
T4A 6.2 22.6 15.6 18.9
T4B 27.7 20.8 26.7 11.6
T1-T4A 4 1.8 4.5 3.3
TX 56.9 22.1 39.9 21.2
N status
N0 18.2 25.2 21.3 38.6
N1 3.2 11.1 6.7 14.3
N2 4.1 20.4 8.4 13
N3A 6.2 14.6 9.9 10.8
N3B 3.2 5.8 5.9 4.4
N1–3 50.7 11.1 34.6 7.5
NX 15.3 11.9 13.1 11.5
AJCC Stage
 0/IA 0 2.7 0 11.9
 IB 0 4 0 9.8
 IIA 0 7.5 0 8.9
 IIB 0 8 0 8.2
 IIIA 0 9.7 0 8.5
 IIIB 0 17.7 0 12.2
 IIIC 0 17.7 0 11.6
 IV 100 0 100 0
 Unknown 0 32.3 0 29.2
Death within 1 year 79.7 42.9 55 29.7
Death within 5 years 96.9 74.3 89.6 62.1
  1. +/+ = true positive, +/− false positive, −/+ false negative, −/− true negative