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Table 2 Summary of systematic review characteristics

From: Integration of care for hypertension and diabetes: a scoping review assessing the evidence from systematic reviews and evaluating reporting

Review Search date Number of studies included Population and country where study was conducted Intervention Comparator Outcomes
Atlantis 2014 [23] August 2013 7 Adults diagnosed with depression and co-morbid diabetes Australia: 1 study USA: 6 studies RCT: 7 Range of number of participants in each study: 58–417 Integrated care: 2 studies Collaborative care: 5 studies Type of integration: Vertical Clinical Usual care: 4 studies Enhanced usual care: 3 studies Depression score outcome • CES-D 20 in 1 study • PHQ-9 in 2 studies • SCL-20 in 4 studies Glycaemic control by HbA1c
Huang 2013 [24] 27 March 2013 8 Patients with depression and diabetes One trial included only African Americans and two trials included only old patients (aged over 50 and 60 year old respectively) USA: all studies RCT: 8 Range of number of participants in each study: 58–417 Integrated management: 2 studies Program to Encourage Active, Rewarding Lives for Seniors (PEARLS): 1 study Multifaceted Diabetes and Depression Program (MDDP): 1 study Collaborative care: 1 study Stepped collaborative care: 1 study An individualized stepped-care depression treatment program: 1 study Improving Mood Promoting Access to Collaborative Treatment (IMPACT): 1 study Type of integration: Vertical Professional Clinical Normal usual care: 5 trials Enhanced usual care: 3 trials Depression treatment response and depression remission at the end of follow-up Depression treatment response at 6 and 12 months follow-up Depression remission at 6 and 12 months follow-up Diabetes clinical outcomes (HbA1c values) at the end of follow-up Diabetes clinical outcomes (HbA1c values) at 6 and 12 months follow-up Adherence to medication (including adherence of oral hypoglycemic agents and/or antidepressants)
Joshi 2014 [25] 26 May – 13 June, 2013 22 total in review; 4 of relevance Task-shifting for the management of hypertension and cardiovascular diseases: 7 studies Task-shifting for the management of diabetes: 5 studies Cameroon: 3 studies South Africa: 1 study Before-after study: 3 RCT:1 Range of number of participants in each study: 221–1343 Task-shifting for the management of non-communicable disease Task shifting from: Physicians to health workers: 4 studies Type of integration: Vertical Professional Clinical Usual healthcare: 4 studies Process outcomes Disease outcomes Treatment concordance Cost-effectiveness Enablers for task-shifting Barriers to task-shifting
Smith 2016 [26] 28 Sept, 2015 18 total in review; 6 of relevance Hypertension and depression: 1 study Depression and diabetes/heart disease: 3 studies Hypertension and diabetes: 2 studies Australia: 1 study UK: 1 study USA: 4 studies Cluster RCT: 1 RCT: 4 RCT (pilot): 1 Range of number of participants in each study: 61–400 Change to organisation of care delivery through case management or enhanced multidisciplinary team work: 5 studies Patient-oriented, such as educational or self-management support-type interventions: 3 study Type of integration: Vertical Professional Clinical Usual care: 2 studies Usual care additional services: 3 studies Enhanced primary care: 1 studies Patient clinical or mental health outcomes Patient-reported outcome measures Utilisation of health services Patient behaviour Provider behaviour Acceptability of the service to recipients and providers, and treatment satisfaction Economic outcomes
Watson 2013 [27] 11 June, 2012 12 studies; 3 studies of relevance Adults (mean age = 59 years) and various chronic medical conditions, including 3 studies of relevance focusing on diabetes and depression USA: all studies RCT: 2 studies Preplanned sub-group analysis from a separate randomized controlled trial: 1 study Range of number of participants in each study: 329–417 All included studies characterized their respective intervention as a form of collaborative care, not another form of a practice-based intervention (such as integrated care) Type of integration: Vertical Professional Clinical Enhanced usual care: 2 studies (9 articles) Usual care: 1 study (2 articles) Mental health outcomes Chronic medical outcomes Harms
  1. RCT randomized controlled trial, USA United States of America