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Table 4 All-cause mortality by treatment period, by gender and age. Cox regression and 95% confidence intervals

From: From restrictive to more liberal: variations in mortality among patients in opioid maintenance treatment over a 12-year period

  In-treatment (n = 6871) After treatment (n = 1650)
HR (95% CI) P-value HR (95% CI) P-value
Treatment period
 1997–1999 (reference)
  2000–2002 0.88 (0.67–1.18) 0.398 0.93 (0.34–2.57) 0.889
  2003–2005 0.71 (0.52–0.97) 0.33 0,56 (0.20–1.56) 0.266
  2006–2009 0.59 (0.39–0.98) 0.11 0.43 (0.51–1.20) 0.106
Gender
 Men (reference)
  Female 0.95 (0.76–2.20) 0.68 0.73 (0.54–1.00) 0.046
  Age Treatment start 1.07 (1.06–1.09) < 0,001 0.99 (0.97–1.01) 0.577
  1. HR Hazard Ratio (estimated Hazard ratio for a one unit increase of change in the explanatory variable given the other variables held constant in the model)