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Table 5 Non-overdose and overdose death in different time-intervals following treatment start (n = 6871) and treatment cessation (n = 1650): crude mortality rates (CMR) per 1000 person-years and 95% confidence interval

From: From restrictive to more liberal: variations in mortality among patients in opioid maintenance treatment over a 12-year period

  1–2 weeks 2–4 weeks 2–6 months 6 months and after
n PY CMR (CI) n PY CMR (CI) n PY CMR (CI) n PY CMR (CI)
After treatment start
 Non-overdose 7 340 20.6 (5.3–35.8) 2 335 6.0 (0.0–14.2) 21 3124 6.7 (3.8–9.6) 348 28,894 12.0 (10.8–13.3)
 Overdose 2 340 5.9 (0.0–14.0) 0 335 0 11 3124 3.5 (1.4–5.6) 147 28,894 5.1 (4.3–5.9)
After treatment stop
 Non-overdose 4 127 31.4 (0.6–62.2) 3 112 26.7 (0.0–56.9) 39 1008 38.7 (26.5–50.8) 184 6700 27.5 (23.5–31.4)
 Overdose 0 127 0 2 112 17.8 (0.0–42.5) 28 1008 27.8 (17.5–38.1) 129 6700 19.3 (15.9–22.6)